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    Paul Stamets' microdosing discovery: Stacking with Lion's Mane, niacin and truffles

    Paul Stamets' microdosing discovery: Stacking with Lion's Mane, niacin and truffles

    Research on microdosing is constantly evolving, and every now and then a discovery is made that can really add a new dimension to the microdosing experience. One such invention is called stacking. Especially the combination of Lion's Mane, Niacin and psilocybin in the form of Microdosing XP truffles is gaining popularity. In this article you will read what stacking is, and how you can use this special combination for extra focus on your microdosing days.

    What is stacking? (Paul Stamets Stack)

    When you follow a stacking protocol, you combine supplements that enhance each other's effects. In this formula, this applies to Niacin and the functional mushroom Lion's Mane. These two substances combined provide, among other things, an improvement in cognitive functions. Combine this with the 'every other day' microdosing protocol using Microdosing XP truffles for a microdosing experience with extra mental capacity. At the cradle of this new stacking, the formula is the well-known mycologist Paul Stamets - known from the excellent Netflix series Fantastic Fungi.

    What is Lion's Mane?

    Lion's Mane is an ancient medicinal mushroom. It is a proven neuroprotectant - meaning it protects brain cells from damage. This mushroom can also improve brain function, fight anxiety and depression, and even promote neurogenesis - the creation of new neurons. In this article, we've listed the benefits of this mushroom and this stacking formula for you. 

    For more information on Microdosing with Lion's Mane, make sure to check out the Microdosing Institute website. They also offer a complete online course, community support and 1:1 guidance during your journey.

    Lion's Mane supports memory and concentration

    The Lion's Mane mushroom is known for its powerful stimulating effect on the brain. For example, it helps stimulate the production of nerve growth factors (NGF).[1] NGF is a neuropeptide that helps maintain neurons - the brain cells responsible for processing and transmitting information. So whether you need to study for an exam, write a paper or focus on your work, Lion's Mane could help.

    Check out the latest research on Lion's Mane here:


    Lion's Mane increases energy levels

    There are several reasons why Lion's Mane can provide more energy. Lion's Mane contains antioxidants that support the overall health of the cells in the body.[2] Because energy transport occurs between cells, more antioxidants in your diet make it easier for your body to produce more energy.

    Lion's Mane has also been shown to reduce lactic acid in the blood - which causes fatigue after intense physical activity. It also increases glycogen levels in tissues, which promotes energy production.[3]

    Lion's Mane supports insulin sensitivity

    Studies show that taking Lion's Mane mushrooms can help improve insulin sensitivity. This means you will need less sugar to get energy, which reduces the risk of diabetes or weight gain. 

    Lion's Mane supports gut health

    Lion's Mane has natural antibacterial properties that help protect the intestines from harmful bacteria, such as Heliobacter pylori - which can cause stomach ulcers.[4] Lion's Mane has also been shown to reduce inflammation in the gastrointestinal system. In Traditional Chinese Medicine, this mushroom has been used for centuries to combat stomach problems, and recent scientific studies seem to confirm these medicinal effects. [5]

    Lion's Mane may help treat obesity

    Animal studies show that the Lion's Mane mushroom can combat obesity. These trials have shown that the supplement reduces the absorption of fats in the body,[6] and it could potentially be an effective weight loss aid for humans.

    Lion's Mane can help with cardiovascular problems

    An ethanol extract of Lion's Mane improved fat metabolism in mice fed a high-fat diet,[7] and this research seems to indicate that it could also help treat or prevent cardiovascular problems in humans. 

    It seems to have been shown that Lion's Mane prevents platelet aggregation associated with thrombosis[8].

    What is Niacin, or Vitamin B3?

    Niacin, or nicotinic acid, has an important role in energy metabolism and protein metabolism. It is the precursor of the nicotinamide moiety of important coenzymes, such as nicotinamide adenine dinucleotide (NAD/NADH and NADP/NADPH), which are involved in a wide range of biochemical reactions, such as the citric acid cycle. Without this vitamin, there can be no proper metabolism, such as the synthesis of proteins, fats and carbohydrates.

    Nicotinic acid has an antioxidant effect and is involved in many enzymatic processes. It is important for the regeneration of the skin, muscles, nerves and DNA.

    The function of Niacin in the microdosing stacking protocol is that it helps the psilocybin and the Lion's Mane diffuse through the body. In particular, it helps to get these agents through the blood-brain barrier, giving them optimal effects. This is where they contribute to cognitive functions, as well as the growth of new brain cells and the creation of new neural connections. So the combination of psilocybin, Lion's Mane and Niacin is ideal if you want to stimulate and optimize the functioning of your brain. 

    You can order the Premium stacking Lion's Mane, Microdosing XP truffles and Niacin here.

    For more information on Microdosing with Lion's Mane, check out the Microdosing Institute website Lions-mane-stacking. They also offer a complete online course, community support and 1:1 guidance during your journey.

    Research Source:

    (1) Stimulates production of nerve growth factors 

    (2) Supports overall health of cells

    (3) Promotes energy production

    (4) Helps protect the gut against harmful bacteria 

    (5) Reduces inflammation in the GI tract

    (6) Treatment of obesity 

    (7) Prevention of cardiovascular problems

    (8) Helps prevent thrombosis

    (9) https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.2634







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